ISA-95 (MES integration)

ISA-95 (ANSI/ISA-95 and IEC 62264) is the international standard that structures vertical integration between production systems (level 0 to 2: sensors, controllers, SCADA), MES (level 3: execution, traceability, batch genealogy, resource management, quality management) and ERP (level 4: planning, finance, supply chain). We use it as a reference framework to specify data exchanges between layers: downstream production orders, upstream production reports, material management, batch release. The standard also defines an exchange format (B2MML, XML based on ISA-95) that standardizes interfaces. On a pharma project, clean ISA-95 integration simplifies audits, accelerates MES commissioning, and limits costly custom developments to validate.